Rössler, Jochen

The selective VEGFR1-3 inhibitor axitinib (AG-013736) shows antitumor activity in human neuroblastoma xenografts. [electronic resource] - International journal of cancer Jun 2011 - 2748-58 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0215

10.1002/ijc.25611 doi


Animals
Apoptosis
Axitinib
Blotting, Western
Bone Marrow Neoplasms--drug therapy
Child
Drug Synergism
Endothelium, Vascular--cytology
Humans
Imidazoles--therapeutic use
Indazoles--therapeutic use
Male
Mice
Mice, Nude
Neovascularization, Pathologic--drug therapy
Neuroblastoma--blood supply
Phosphorylation
Sirolimus--pharmacology
Stem Cells--drug effects
Tumor Cells, Cultured
Vascular Endothelial Growth Factor Receptor-1--antagonists & inhibitors
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors
Vascular Endothelial Growth Factor Receptor-3--antagonists & inhibitors
Xenograft Model Antitumor Assays