The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel. [electronic resource]
- BMC medical genomics Aug 2010
- 37 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1755-8794
10.1186/1755-8794-3-37 doi
Antineoplastic Agents--toxicity Arsenic Trioxide Arsenicals Biomarkers, Tumor--genetics Cell Line, Tumor Humans Leukemia, Promyelocytic, Acute--etiology NF-E2-Related Factor 2--genetics National Cancer Institute (U.S.) Oxidative Stress Oxides--toxicity RNA Interference United States