TY - GEN AU - Correale,Pierpaolo AU - Remondo,Cinzia AU - Carbone,Salvatore Francesco AU - Ricci,Veronica AU - Migali,Cristina AU - Martellucci,Ignazio AU - Licchetta,Antonella AU - Addeo,Raffaele AU - Volterrani,Luca AU - Gotti,Giuseppe AU - Rotundo,Maria Saveria AU - Tassone,Pierfrancesco AU - Sperlongano,Pasquale AU - Abbruzzese,Alberto AU - Caraglia,Michele AU - Tagliaferri,Pierosandro AU - Francini,Guido TI - Dose/dense metronomic chemotherapy with fractioned cisplatin and oral daily etoposide enhances the anti-angiogenic effects of bevacizumab and has strong antitumor activity in advanced non-small-cell-lung cancer patients SN - 1555-8576 PY - 2010///1207 KW - Adenocarcinoma KW - blood KW - Administration, Oral KW - Adult KW - Aged KW - Aged, 80 and over KW - Angiopoietin-1 KW - Antibodies, Monoclonal KW - administration & dosage KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Bevacizumab KW - Carcinoma, Non-Small-Cell Lung KW - Carcinoma, Squamous Cell KW - Cisplatin KW - Drug Synergism KW - Enzyme-Linked Immunosorbent Assay KW - Etoposide KW - Female KW - Humans KW - Lung Neoplasms KW - Male KW - Maximum Tolerated Dose KW - Middle Aged KW - Prospective Studies KW - Survival Rate KW - Thrombospondins KW - Treatment Outcome KW - Vascular Endothelial Growth Factor A N1 - Publication Type: Clinical Trial, Phase I; Journal Article UR - https://doi.org/10.4161/cbt.9.9.11441 ER -