TY  - GEN
AU  - Poulogiannis,George
AU  - McIntyre,Rebecca E
AU  - Dimitriadi,Maria
AU  - Apps,John R
AU  - Wilson,Catherine H
AU  - Ichimura,Koichi
AU  - Luo,Feijun
AU  - Cantley,Lewis C
AU  - Wyllie,Andrew H
AU  - Adams,David J
AU  - Arends,Mark J
TI  - PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
SN  - 1091-6490
PY  - 2010///0923
KW  - Adenomatous Polyposis Coli
KW  - etiology
KW  - Animals
KW  - Base Sequence
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Chromosomes, Human, Pair 6
KW  - genetics
KW  - Cocarcinogenesis
KW  - Colorectal Neoplasms
KW  - DNA Methylation
KW  - DNA Primers
KW  - DNA, Neoplasm
KW  - chemistry
KW  - Gene Deletion
KW  - Gene Dosage
KW  - Genes, APC
KW  - Genes, Tumor Suppressor
KW  - Heterozygote
KW  - Humans
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mice, Mutant Strains
KW  - Models, Molecular
KW  - Mutation
KW  - Spectral Karyotyping
KW  - Ubiquitin-Protein Ligases
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1009941107
ER  -