TY - GEN AU - Smith,Alexander E AU - Mohamedali,Azim M AU - Kulasekararaj,Austin AU - Lim,ZiYi AU - Gäken,Joop AU - Lea,Nicholas C AU - Przychodzen,Bartlomiej AU - Mian,Syed A AU - Nasser,Erick E AU - Shooter,Claire AU - Westwood,Nigel B AU - Strupp,Corinna AU - Gattermann,Norbert AU - Maciejewski,Jaroslaw P AU - Germing,Ulrich AU - Mufti,Ghulam J TI - Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value SN - 1528-0020 PY - 2010///1216 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Amino Acid Substitution KW - Base Sequence KW - Cell Differentiation KW - genetics KW - DNA Mutational Analysis KW - DNA-Binding Proteins KW - Dioxygenases KW - Female KW - Gene Expression KW - Humans KW - Janus Kinase 2 KW - Karyotyping KW - Leukemia, Myelomonocytic, Chronic KW - Loss of Heterozygosity KW - Male KW - Middle Aged KW - Molecular Sequence Data KW - Mutation KW - Myelodysplastic Syndromes KW - Polymorphism, Single Nucleotide KW - Prognosis KW - Proto-Oncogene Proteins KW - RNA, Messenger KW - RNA, Neoplasm KW - Survival Analysis KW - T-Lymphocytes KW - metabolism KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2010-03-274704 ER -