TY - GEN AU - Zietsch,Jan AU - Ziegenhagen,Nicolas AU - Heppner,Frank L AU - Reuss,David AU - von Deimling,Andreas AU - Holtkamp,Nikola TI - The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment SN - 1932-6203 PY - 2010///1028 KW - Antineoplastic Agents KW - therapeutic use KW - Apoptosis KW - Blotting, Western KW - Cell Line, Tumor KW - Humans KW - Immunohistochemistry KW - In Vitro Techniques KW - Indoles KW - Nerve Sheath Neoplasms KW - drug therapy KW - Proto-Oncogene Proteins c-kit KW - genetics KW - Pyrroles KW - Receptor, Platelet-Derived Growth Factor alpha KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - drug effects KW - Sunitinib KW - Vascular Endothelial Growth Factor A KW - Vascular Endothelial Growth Factor Receptor-2 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0011858 ER -