The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment. [electronic resource]
- PloS one Jul 2010
- e11858 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0011858 doi
Antineoplastic Agents--therapeutic use Apoptosis Blotting, Western Cell Line, Tumor Humans Immunohistochemistry In Vitro Techniques Indoles--therapeutic use Nerve Sheath Neoplasms--drug therapy Proto-Oncogene Proteins c-kit--genetics Pyrroles--therapeutic use Receptor, Platelet-Derived Growth Factor alpha--genetics Reverse Transcriptase Polymerase Chain Reaction Signal Transduction--drug effects Sunitinib Vascular Endothelial Growth Factor A--genetics Vascular Endothelial Growth Factor Receptor-2--genetics