Martins, Paulo J F

Central nervous system delivery of the antipsychotic olanzapine induces hepatic insulin resistance. [electronic resource] - Diabetes Oct 2010 - 2418-25 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1939-327X

10.2337/db10-0449 doi


Animals
Antipsychotic Agents--administration & dosage
Benzodiazepines--administration & dosage
Blood Glucose--drug effects
Carotid Arteries--physiopathology
DNA Primers
Glucose Clamp Technique
Glucose-6-Phosphatase--drug effects
Hyperinsulinism--physiopathology
Infusions, Intravenous
Injections, Intraventricular
Insulin Resistance--physiology
Intracellular Signaling Peptides and Proteins--drug effects
Jugular Veins--physiopathology
Kinetics
Liver--drug effects
Male
Neuropeptides--drug effects
Olanzapine
Orexins
Pro-Opiomelanocortin--drug effects
Rats
Rats, Sprague-Dawley
Tubulin--drug effects