Amoruso, Angela <br/><br/>
The nitric oxide-donating pravastatin, NCX 6550, inhibits cytokine release and NF-κB activation while enhancing PPARγ expression in human monocyte/macrophages.  [electronic resource] 

 -  Pharmacological research  Nov 2010 
 - 391-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1096-1186 
<br/><br/><label>Standard No.: </label>10.1016/j.phrs.2010.07.006  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--pharmacology<br/>Cytokines--metabolism<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Interleukin-6--metabolism<br/>Macrophages--cytology<br/>Mice<br/>Monocytes--drug effects<br/>NF-kappa B--antagonists & inhibitors<br/>Nitrates--pharmacology<br/>Nitric Oxide--metabolism<br/>Nitric Oxide Donors--pharmacology<br/>PPAR gamma--metabolism<br/>Pravastatin--analogs & derivatives<br/>Superoxides--metabolism<br/>Tumor Necrosis Factor-alpha--metabolism