Rajamäki, Kristiina <br/><br/>
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation.  [electronic resource] 

 -  PloS one  Jul 2010 
 - e11765 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0011765  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Blotting, Western<br/>Carrier Proteins--genetics<br/>Caspase 1--metabolism<br/>Caspase Inhibitors<br/>Cathepsin B--metabolism<br/>Cells, Cultured<br/>Cholesterol--chemistry<br/>Chromatography, Thin Layer<br/>Cytochalasin D--pharmacology<br/>Cytoplasm--metabolism<br/>Humans<br/>Inflammation--genetics<br/>Interleukin-1beta--metabolism<br/>Lipopolysaccharides--pharmacology<br/>Lysosomes--drug effects<br/>Macrophages--drug effects<br/>Microscopy, Confocal<br/>Monocytes--drug effects<br/>NLR Family, Pyrin Domain-Containing 3 Protein<br/>Phagocytosis--drug effects<br/>Potassium--metabolism<br/>RNA, Small Interfering--genetics<br/>Reverse Transcriptase Polymerase Chain Reaction