Green, Alexa S <br/><br/>
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.  [electronic resource] 

 -  Blood  Nov 2010 
 - 4262-73 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1528-0020 
<br/><br/><label>Standard No.: </label>10.1182/blood-2010-02-269837  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>AMP-Activated Protein Kinase Kinases<br/>Adaptor Proteins, Signal Transducing--metabolism<br/>Animals<br/>Biocatalysis--drug effects<br/>Cell Cycle Proteins<br/>Cell Death--drug effects<br/>Cell Proliferation--drug effects<br/>Enzyme Activation--drug effects<br/>Hematopoietic Stem Cells--cytology<br/>Humans<br/>Leukemia, Myeloid, Acute--enzymology<br/>Metformin--pharmacology<br/>Mice<br/>Neoplasm Proteins--biosynthesis<br/>Phosphoproteins--metabolism<br/>Phosphorylation--drug effects<br/>Polyribosomes--drug effects<br/>Protein Biosynthesis--drug effects<br/>Protein Kinases--metabolism<br/>Protein Serine-Threonine Kinases--metabolism<br/>Signal Transduction--drug effects<br/>TOR Serine-Threonine Kinases--metabolism<br/>Tuberous Sclerosis Complex 2 Protein<br/>Tumor Suppressor Proteins--metabolism