Facchino, Sabrina

BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jul 2010 - 10096-111 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.1634-10.2010 doi


AC133 Antigen
Antigens, CD--metabolism
Brain Neoplasms--pathology
Cell Line, Tumor
Cell Transformation, Neoplastic--pathology
Checkpoint Kinase 2
Chromatography, Liquid--methods
Comet Assay--methods
DNA Breaks, Double-Stranded--radiation effects
DNA Damage--physiology
DNA-Binding Proteins--metabolism
Embryonic Stem Cells--physiology
Fetus
Flow Cytometry--methods
Glioblastoma--pathology
Glycoproteins--metabolism
Green Fluorescent Proteins--genetics
Humans
Immunoprecipitation--methods
Neoplastic Stem Cells--physiology
Nuclear Proteins--genetics
Peptides--metabolism
Phosphorylation--genetics
Polycomb Repressive Complex 1
Polycomb-Group Proteins
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins--genetics
Radiation Tolerance
Reactive Oxygen Species--metabolism
Repressor Proteins--genetics
Tandem Mass Spectrometry--methods
Transfection--methods