Niculescu-Duvaz, Dan <br/><br/>
Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Sep 2010 
 - 6934-52 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2010.06.031  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Binding Sites<br/>Computer Simulation<br/>Female<br/>Furans--chemistry<br/>Humans<br/>Imidazoles--chemistry<br/>Mice<br/>Mutation<br/>Protein Kinase Inhibitors--chemical synthesis<br/>Protein Structure, Tertiary<br/>Proto-Oncogene Proteins B-raf--antagonists & inhibitors<br/>Pyrazoles--chemical synthesis<br/>Structure-Activity Relationship