Molecular modeling approaches in the discovery of new drugs for anti-cancer therapy: the investigation of p53-MDM2 interaction and its inhibition by small molecules. [electronic resource]
- Current medicinal chemistry 2010
- 3142-54 p. digital
Publication Type: Journal Article; Review
1875-533X
10.2174/092986710792232021 doi
Antineoplastic Agents--chemistry Benzodiazepinones--chemistry Drug Design Humans Imidazolines--chemistry Indoles--chemistry Molecular Dynamics Simulation Neoplasms--drug therapy Oxindoles Protein Structure, Tertiary Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors Tumor Suppressor Protein p53--antagonists & inhibitors