Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study. [electronic resource]
- The Journal of infectious diseases Sep 2010
- 717-22 p. digital
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1537-6613
10.1086/655470 doi
ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics Alkynes Anti-HIV Agents--pharmacokinetics Aryl Hydrocarbon Hydroxylases--genetics Benzoxazines--pharmacokinetics Black People Cyclopropanes Cytochrome P-450 CYP2B6 Cytochrome P-450 CYP3A--genetics Female HIV Infections--drug therapy Hispanic or Latino Humans Male Oxidoreductases, N-Demethylating--genetics Pharmacogenetics Polymorphism, Single Nucleotide Reverse Transcriptase Inhibitors--pharmacokinetics Treatment Outcome White People