Day, James E H

Inhibition of Hsp90 with resorcylic acid macrolactones: synthesis and binding studies. [electronic resource] - Chemistry (Weinheim an der Bergstrasse, Germany) Sep 2010 - 10366-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-3765

10.1002/chem.201001119 doi


Antineoplastic Agents--chemical synthesis
Binding Sites
Cell Line, Tumor
Crystallography, X-Ray
HSP90 Heat-Shock Proteins--antagonists & inhibitors
Humans
Macrocyclic Compounds--chemical synthesis
Macrolides--chemical synthesis
Molecular Conformation
Neoplasms--drug therapy
Protein Binding