Type 1 diabetes in BioBreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Aug 2010
- 2285-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1550-6606
10.4049/jimmunol.1000462 doi
Adoptive Transfer Animals Cell Line Diabetes Mellitus, Type 1--genetics Female Flow Cytometry GTP-Binding Proteins--genetics Green Fluorescent Proteins--genetics Humans Interleukin-17--immunology Interleukin-2 Receptor alpha Subunit--immunology Lymphocyte Count Lymphopenia--genetics Male Mutation Rats Rats, Inbred BB Rats, Transgenic Receptors, Antigen, T-Cell--immunology T-Lymphocytes--immunology T-Lymphocytes, Helper-Inducer--immunology T-Lymphocytes, Regulatory--immunology