Madonna, Stefania <br/><br/>
The IFN-gamma-dependent suppressor of cytokine signaling 1 promoter activity is positively regulated by IFN regulatory factor-1 and Sp1 but repressed by growth factor independence-1b and Krüppel-like factor-4, and it is dysregulated in psoriatic keratinocytes.  [electronic resource] 

 -  Journal of immunology (Baltimore, Md. : 1950)  Aug 2010 
 - 2467-81 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1550-6606 
<br/><br/><label>Standard No.: </label>10.4049/jimmunol.1001426  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Binding Sites--genetics<br/>Cells, Cultured<br/>Chromatin Immunoprecipitation<br/>DNA-Binding Proteins--genetics<br/>Gene Expression Regulation--drug effects<br/>Humans<br/>Immunoblotting<br/>Interferon Regulatory Factor-1--genetics<br/>Interferon-gamma--pharmacology<br/>Keratinocytes--drug effects<br/>Kruppel-Like Factor 4<br/>Kruppel-Like Transcription Factors--genetics<br/>Luciferases--genetics<br/>Promoter Regions, Genetic--genetics<br/>Protein Binding--drug effects<br/>Proto-Oncogene Proteins--genetics<br/>Psoriasis--genetics<br/>Repressor Proteins--genetics<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Sp1 Transcription Factor--genetics<br/>Suppressor of Cytokine Signaling 1 Protein<br/>Suppressor of Cytokine Signaling Proteins--genetics<br/>Time Factors<br/>Transfection