Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. [electronic resource]
- Toxicological sciences : an official journal of the Society of Toxicology Oct 2010
- 348-58 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1096-0929
10.1093/toxsci/kfq220 doi
Cells, Cultured Dose-Response Relationship, Drug Female Gas Chromatography-Mass Spectrometry Hepatocytes--drug effects High-Throughput Screening Assays--methods Humans Male Metabolic Clearance Rate Protein Binding--drug effects Risk Assessment Toxicity Tests Xenobiotics--classification