TY  - GEN
AU  - Katz,E
AU  - Dubois-Marshall,S
AU  - Sims,A H
AU  - Faratian,D
AU  - Li,J
AU  - Smith,E S
AU  - Quinn,J A
AU  - Edward,M
AU  - Meehan,R R
AU  - Evans,E E
AU  - Langdon,S P
AU  - Harrison,D J
TI  - A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk
SN  - 1532-1827
PY  - 2010///0916
KW  - Antibodies, Monoclonal
KW  - therapeutic use
KW  - Antibodies, Monoclonal, Humanized
KW  - Antigens, CD
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Cadherins
KW  - genetics
KW  - Cell Line, Tumor
KW  - Colony-Forming Units Assay
KW  - DNA Primers
KW  - Down-Regulation
KW  - Female
KW  - Gene Amplification
KW  - Genes, erbB-2
KW  - Humans
KW  - Immunohistochemistry
KW  - Intracellular Signaling Peptides and Proteins
KW  - antagonists & inhibitors
KW  - Neoplasm Proteins
KW  - Oligonucleotide Array Sequence Analysis
KW  - Open Reading Frames
KW  - Protein-Tyrosine Kinases
KW  - RNA, Messenger
KW  - Receptor, ErbB-2
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Syk Kinase
KW  - Transfection
KW  - Trastuzumab
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/sj.bjc.6605763
ER  -