Sewgobind, V D K D

The Jak inhibitor CP-690,550 preserves the function of CD4CD25FoxP3 regulatory T cells and inhibits effector T cells. [electronic resource] - American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Aug 2010 - 1785-95 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't

1600-6143

10.1111/j.1600-6143.2010.03200.x doi


CD4-Positive T-Lymphocytes--drug effects
Female
Humans
Interleukin-2--pharmacology
Interleukin-2 Receptor alpha Subunit--immunology
Kidney Transplantation--immunology
Male
Middle Aged
Piperidines
Pyrimidines--pharmacology
Pyrroles--pharmacology
STAT5 Transcription Factor--antagonists & inhibitors
T-Lymphocytes--drug effects
T-Lymphocytes, Regulatory--drug effects