TY  - GEN
AU  - Elcombe,Clifford R
AU  - Elcombe,Barbara M
AU  - Foster,John R
AU  - Farrar,David G
AU  - Jung,Reinhard
AU  - Chang,Shu-Ching
AU  - Kennedy,Gerald L
AU  - Butenhoff,John L
TI  - Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats following dietary exposure to ammonium perfluorooctanoate occurs through increased activation of the xenosensor nuclear receptors PPARα and CAR/PXR
SN  - 1432-0738
PY  - 2010///1103
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Body Weight
KW  - Caprylates
KW  - toxicity
KW  - Cell Proliferation
KW  - Constitutive Androstane Receptor
KW  - Cytochrome P-450 Enzyme System
KW  - metabolism
KW  - DNA
KW  - Environmental Pollutants
KW  - Fluorocarbons
KW  - Hepatocytes
KW  - Hepatomegaly
KW  - chemically induced
KW  - Hypertrophy
KW  - Liver
KW  - enzymology
KW  - Male
KW  - Organ Size
KW  - PPAR alpha
KW  - Peroxisomes
KW  - Pregnane X Receptor
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Receptors, Steroid
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00204-010-0572-2
ER  -