TY - GEN AU - Farina,Giuseppina A AU - York,Michael R AU - Di Marzio,Michael AU - Collins,Cindy A AU - Meller,Stephan AU - Homey,Bernhard AU - Rifkin,Ian R AU - Marshak-Rothstein,Ann AU - Radstake,Timothy R D J AU - Lafyatis,Robert TI - Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis SN - 1523-1747 PY - 2010///1116 KW - Adaptor Proteins, Vesicular Transport KW - genetics KW - Animals KW - Cells, Cultured KW - Dermatitis KW - Dermis KW - immunology KW - Disease Models, Animal KW - Fibroblasts KW - cytology KW - GTP-Binding Proteins KW - metabolism KW - Gene Expression KW - Humans KW - Interferon Type I KW - Interferon-gamma KW - Lupus Erythematosus, Cutaneous KW - Mice KW - Mice, Inbred C57BL KW - Mice, Mutant Strains KW - Myxovirus Resistance Proteins KW - Poly I-C KW - Scleroderma, Systemic KW - Toll-Like Receptor 3 KW - agonists KW - Transforming Growth Factor beta N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/jid.2010.200 ER -