TY - GEN AU - Ariyoshi,Noritaka AU - Iga,Yukako AU - Hirata,Koji AU - Sato,Yasunori AU - Miura,Go AU - Ishii,Itsuko AU - Nagamori,Seiji AU - Kitada,Mitsukazu TI - Enhanced susceptibility of HLA-mediated ticlopidine-induced idiosyncratic hepatotoxicity by CYP2B6 polymorphism in Japanese SN - 1880-0920 PY - 2010///1012 KW - Aryl Hydrocarbon Hydroxylases KW - genetics KW - Biotransformation KW - Case-Control Studies KW - Chemical and Drug Induced Liver Injury KW - epidemiology KW - Cytochrome P-450 CYP2B6 KW - Enzyme Activation KW - drug effects KW - Genotype KW - HLA Antigens KW - Haplotypes KW - Humans KW - Japan KW - Oxidoreductases, N-Demethylating KW - Platelet Aggregation Inhibitors KW - adverse effects KW - Polymorphism, Single Nucleotide KW - Ticlopidine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2133/dmpk.25.298 ER -