TY - GEN AU - Getachew,Robel AU - Ballinger,Mandy L AU - Burch,Micah L AU - Reid,Julianne J AU - Khachigian,Levon M AU - Wight,Thomas N AU - Little,Peter J AU - Osman,Narin TI - PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL SN - 1945-7170 PY - 2010///1004 KW - Animals KW - Aorta KW - drug effects KW - Apolipoproteins E KW - genetics KW - Benzamides KW - Biglycan KW - Cells, Cultured KW - Dietary Fats KW - administration & dosage KW - Extracellular Matrix Proteins KW - metabolism KW - Extracellular Signal-Regulated MAP Kinases KW - Glycosaminoglycans KW - Humans KW - Imatinib Mesylate KW - Lipids KW - analysis KW - Lipoproteins, LDL KW - Male KW - Mice KW - Mice, Knockout KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Muscle, Smooth, Vascular KW - cytology KW - Phosphorylation KW - Piperazines KW - pharmacology KW - Platelet-Derived Growth Factor KW - Protein Binding KW - Protein Kinase Inhibitors KW - Protein-Tyrosine Kinases KW - antagonists & inhibitors KW - Proteoglycans KW - Pyrimidines KW - RNA Interference KW - Receptor, Platelet-Derived Growth Factor beta N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1210/en.2010-0027 ER -