A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. [electronic resource]
- Blood Oct 2010
- 2826-35 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1528-0020
10.1182/blood-2010-03-275776 doi
Anemia, Diamond-Blackfan--blood Animals Base Sequence DNA Primers--genetics Disease Models, Animal Erythroid Precursor Cells--pathology Erythropoiesis--genetics Female Gene Expression Profiling Humans Male Mice Mice, Transgenic Mutation, Missense Point Mutation Pregnancy RNA, Messenger--genetics Ribosomal Proteins--genetics