Sánchez, Yolanda

Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. [electronic resource] - The Journal of pharmacology and experimental therapeutics Oct 2010 - 114-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0103

10.1124/jpet.110.168344 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Apoptosis Regulatory Proteins--antagonists & inhibitors
Arsenic Trioxide
Arsenicals--pharmacology
Blotting, Western
Cell Survival--drug effects
Curcumin--pharmacology
Electrophoretic Mobility Shift Assay
Flow Cytometry
Glutathione--metabolism
HL-60 Cells
Humans
Indazoles--pharmacology
Membrane Potentials--drug effects
Mitochondria--drug effects
Oxidants--pharmacology
Oxides--pharmacology
Protein Kinase Inhibitors--pharmacology
Protein Kinases--metabolism
Proto-Oncogene Proteins c-akt--biosynthesis
Reactive Oxygen Species--metabolism
U937 Cells