TY - GEN AU - Avvaru,Balendu Sankara AU - Wagner,Jason M AU - Maresca,Alfonso AU - Scozzafava,Andrea AU - Robbins,Arthur H AU - Supuran,Claudiu T AU - McKenna,Robert TI - Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors SN - 1464-3405 PY - 2010///1123 KW - Acetazolamide KW - analogs & derivatives KW - Animals KW - Binding Sites KW - Carbonic Anhydrase II KW - antagonists & inhibitors KW - Carbonic Anhydrase Inhibitors KW - chemistry KW - Computer Simulation KW - Crystallography, X-Ray KW - Humans KW - Hydrophobic and Hydrophilic Interactions KW - Mice KW - Protein Isoforms KW - Sulfonamides N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bmcl.2010.06.082 ER -