TY  - GEN
AU  - Bruyère,Arnaud
AU  - Declèves,Xavier
AU  - Bouzom,Francois
AU  - Ball,Kathryn
AU  - Marques,Catie
AU  - Treton,Xavier
AU  - Pocard,Marc
AU  - Valleur,Patrice
AU  - Bouhnik,Yoram
AU  - Panis,Yves
AU  - Scherrmann,Jean-Michel
AU  - Mouly,Stephane
TI  - Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass
SN  - 1543-8392
PY  - 2013///0529
KW  - ATP Binding Cassette Transporter, Subfamily B
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - metabolism
KW  - ATP Binding Cassette Transporter, Subfamily G, Member 2
KW  - ATP-Binding Cassette Transporters
KW  - Administration, Oral
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Biological Availability
KW  - Cytochrome P-450 CYP3A
KW  - Humans
KW  - Intestinal Absorption
KW  - Intestine, Small
KW  - Microsomes
KW  - Middle Aged
KW  - Models, Biological
KW  - Neoplasm Proteins
KW  - Pharmacokinetics
KW  - Tissue Distribution
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/mp100015x
ER  -