TY  - GEN
AU  - He,Shuwen
AU  - Ye,Zhixiong
AU  - Dobbelaar,Peter H
AU  - Sebhat,Iyassu K
AU  - Guo,Liangqin
AU  - Liu,Jian
AU  - Jian,Tianying
AU  - Lai,Yingjie
AU  - Franklin,Christopher L
AU  - Bakshi,Raman K
AU  - Dellureficio,James P
AU  - Hong,Qingmei
AU  - Weinberg,David H
AU  - Macneil,Tanya
AU  - Tang,Rui
AU  - Strack,Alison M
AU  - Tamvakopoulos,Constantin
AU  - Peng,Qianping
AU  - Miller,Randy R
AU  - Stearns,Ralph A
AU  - Chen,Howard Y
AU  - Chen,Airu S
AU  - Fong,Tung M
AU  - Wyvratt,Matthew J
AU  - Nargund,Ravi P
TI  - Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity
SN  - 1464-3405
PY  - 2010///1123
KW  - Amides
KW  - chemistry
KW  - Animals
KW  - Anti-Obesity Agents
KW  - Body Weight
KW  - drug effects
KW  - Humans
KW  - Mice
KW  - Mice, Knockout
KW  - Obesity
KW  - drug therapy
KW  - Pyrrolidines
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Receptor, Melanocortin, Type 4
KW  - agonists
KW  - Spiro Compounds
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2010.06.062
ER  -