MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation. [electronic resource]
- Journal of neuro-oncology Feb 2011
- 405-17 p. digital
Publication Type: Journal Article
1573-7373
10.1007/s11060-010-0274-x doi
Adult Astrocytoma--genetics Brain Neoplasms--genetics DNA Methylation DNA Modification Methylases--genetics DNA Repair Enzymes--genetics Disease Progression Female Gene Expression Regulation, Neoplastic Humans Male Middle Aged Mutation--genetics Prognosis Promoter Regions, Genetic--genetics Tumor Suppressor Protein p53--genetics Tumor Suppressor Proteins--genetics