Wang, Wen-Jeng <br/><br/>
Acurhagin-C, an ECD disintegrin, inhibits integrin alphavbeta3-mediated human endothelial cell functions by inducing apoptosis via caspase-3 activation.  [electronic resource] 

 -  British journal of pharmacology  Jul 2010 
 - 1338-51 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-5381 
<br/><br/><label>Standard No.: </label>10.1111/j.1476-5381.2010.00781.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Anoikis--drug effects<br/>Apoptosis--drug effects<br/>Caspase 3--drug effects<br/>Cell Survival--drug effects<br/>Disintegrins--administration & dosage<br/>Dose-Response Relationship, Drug<br/>Endothelial Cells--drug effects<br/>Focal Adhesion Protein-Tyrosine Kinases--drug effects<br/>Humans<br/>Integrin alphaVbeta3--antagonists & inhibitors<br/>Peptide Fragments--administration & dosage<br/>Phosphatidylinositol 3-Kinases--drug effects<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Signal Transduction--drug effects<br/>Umbilical Veins--cytology