TY - GEN AU - Taylor,Matthew D AU - Sadhukhan,Sanjoy AU - Kottangada,Ponnappa AU - Ramgopal,Archana AU - Sarkar,Koustav AU - D'Silva,Sheryl AU - Selvakumar,Annamalai AU - Candotti,Fabio AU - Vyas,Yatin M TI - Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome SN - 1946-6242 PY - 2010///1202 KW - Actins KW - metabolism KW - Cell Differentiation KW - Cell Nucleus KW - Cells, Cultured KW - Cellular Reprogramming KW - genetics KW - Chromatin KW - DNA KW - Epigenesis, Genetic KW - Genetic Loci KW - Genome, Human KW - Histones KW - Humans KW - Immunity KW - immunology KW - Methylation KW - Mutant Proteins KW - Promoter Regions, Genetic KW - Protein Binding KW - Protein Transport KW - T-Box Domain Proteins KW - Th1 Cells KW - cytology KW - Transcription, Genetic KW - Wiskott-Aldrich Syndrome KW - Wiskott-Aldrich Syndrome Protein KW - deficiency KW - T-bet Transcription Factor N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.1126/scitranslmed.3000813 ER -