Sriram, Dharmarajan <br/><br/>
5-Nitro-2,6-dioxohexahydro-4-pyrimidinecarboxamides: synthesis, in vitro antimycobacterial activity, cytotoxicity, and isocitrate lyase inhibition studies.  [electronic resource] 

 -  Journal of enzyme inhibition and medicinal chemistry  Dec 2010 
 - 765-72 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1475-6374 
<br/><br/><label>Standard No.: </label>10.3109/14756360903425221  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Bacterial Agents--chemical synthesis<br/>Antitubercular Agents--chemistry<br/>Bacterial Proteins--antagonists & inhibitors<br/>Chlorocebus aethiops<br/>Computer Simulation<br/>Drug Evaluation, Preclinical<br/>Drug Resistance, Multiple, Bacterial<br/>Enzyme Inhibitors--chemical synthesis<br/>Inhibitory Concentration 50<br/>Isocitrate Lyase--antagonists & inhibitors<br/>Ligands<br/>Microbial Sensitivity Tests<br/>Molecular Structure<br/>Mycobacterium--drug effects<br/>Mycobacterium smegmatis--drug effects<br/>Mycobacterium tuberculosis--drug effects<br/>Piperazines<br/>Protein Binding<br/>Pyrimidines--chemical synthesis<br/>Quinolines<br/>Tuberculosis--drug therapy<br/>Vero Cells