Zhang, Xu-Feng

A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. [electronic resource] - Neuropharmacology Sep 2010 - 201-7 p. digital

Publication Type: Journal Article

1873-7064

10.1016/j.neuropharm.2010.05.009 doi


Animals
Biophysics
Cells, Cultured
Disease Models, Animal
Dose-Response Relationship, Drug
Electric Stimulation--methods
Ganglia, Spinal--cytology
Humans
Hyperalgesia--drug therapy
Male
Membrane Potentials--drug effects
Morpholines--chemistry
NAV1.8 Voltage-Gated Sodium Channel
Neuralgia--complications
Niacinamide--analogs & derivatives
Pain Threshold--drug effects
Patch-Clamp Techniques--methods
Rats
Rats, Sprague-Dawley
Sensory Receptor Cells--drug effects
Sodium Channel Blockers--chemistry
Sodium Channels--drug effects
Spinal Cord Injuries--complications
Tetrodotoxin--pharmacology
Transfection--methods