TY  - GEN
AU  - Hanada,Kazuhiko
AU  - Suda,Makoto
AU  - Kanai,Norihito
AU  - Ogata,Hiroyasu
TI  - Pharmacokinetics and toxicodynamics of oxaliplatin in rats: application of a toxicity factor to explain differences in the nephrotoxicity and myelosuppression induced by oxaliplatin and the other platinum antitumor derivatives
SN  - 1573-904X
PY  - 2010///1221
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacokinetics
KW  - Area Under Curve
KW  - Blood Urea Nitrogen
KW  - Bone Marrow
KW  - drug effects
KW  - Dose-Response Relationship, Drug
KW  - Drug Stability
KW  - Hydrolysis
KW  - Infusions, Intravenous
KW  - Injections, Intravenous
KW  - Kidney
KW  - Male
KW  - Metabolic Clearance Rate
KW  - Models, Biological
KW  - Molecular Structure
KW  - Organoplatinum Compounds
KW  - Oxaliplatin
KW  - Platelet Count
KW  - Rats
KW  - Rats, Wistar
KW  - Time Factors
KW  - Tissue Distribution
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1007/s11095-010-0189-4
ER  -