Hanada, Kazuhiko <br/><br/>
Pharmacokinetics and toxicodynamics of oxaliplatin in rats: application of a toxicity factor to explain differences in the nephrotoxicity and myelosuppression induced by oxaliplatin and the other platinum antitumor derivatives.  [electronic resource] 

 -  Pharmaceutical research  Sep 2010 
 - 1893-9 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1573-904X 
<br/><br/><label>Standard No.: </label>10.1007/s11095-010-0189-4  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacokinetics<br/>Area Under Curve<br/>Blood Urea Nitrogen<br/>Bone Marrow--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Stability<br/>Hydrolysis<br/>Infusions, Intravenous<br/>Injections, Intravenous<br/>Kidney--drug effects<br/>Male<br/>Metabolic Clearance Rate<br/>Models, Biological<br/>Molecular Structure<br/>Organoplatinum Compounds--pharmacokinetics<br/>Oxaliplatin<br/>Platelet Count<br/>Rats<br/>Rats, Wistar<br/>Time Factors<br/>Tissue Distribution