TY  - GEN
AU  - Yip,Calvin K
AU  - Murata,Kazuyoshi
AU  - Walz,Thomas
AU  - Sabatini,David M
AU  - Kang,Seong A
TI  - Structure of the human mTOR complex I and its implications for rapamycin inhibition
SN  - 1097-4164
PY  - 2010///0629
KW  - Adaptor Proteins, Signal Transducing
KW  - Antibiotics, Antineoplastic
KW  - chemistry
KW  - Cell Line
KW  - Computer Simulation
KW  - Cryoelectron Microscopy
KW  - Humans
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Models, Molecular
KW  - Multiprotein Complexes
KW  - Protein Multimerization
KW  - Protein Structure, Quaternary
KW  - Protein Structure, Tertiary
KW  - Protein Subunits
KW  - Proteins
KW  - Regulatory-Associated Protein of mTOR
KW  - Sirolimus
KW  - TOR Serine-Threonine Kinases
KW  - Tacrolimus Binding Protein 1A
KW  - Transcription Factors
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1016/j.molcel.2010.05.017
ER  -