Structure of the human mTOR complex I and its implications for rapamycin inhibition. [electronic resource]
- Molecular cell Jun 2010
- 768-74 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1097-4164
10.1016/j.molcel.2010.05.017 doi
Adaptor Proteins, Signal Transducing Antibiotics, Antineoplastic--chemistry Cell Line Computer Simulation Cryoelectron Microscopy Humans Mechanistic Target of Rapamycin Complex 1 Models, Molecular Multiprotein Complexes Protein Multimerization Protein Structure, Quaternary Protein Structure, Tertiary Protein Subunits--chemistry Proteins--chemistry Regulatory-Associated Protein of mTOR Sirolimus--chemistry TOR Serine-Threonine Kinases Tacrolimus Binding Protein 1A--chemistry Transcription Factors--antagonists & inhibitors