TY - GEN AU - Salphati,Laurent AU - Wong,Harvey AU - Belvin,Marcia AU - Bradford,Delia AU - Edgar,Kyle A AU - Prior,Wei Wei AU - Sampath,Deepak AU - Wallin,Jeffrey J TI - Pharmacokinetic-pharmacodynamic modeling of tumor growth inhibition and biomarker modulation by the novel phosphatidylinositol 3-kinase inhibitor GDC-0941 SN - 1521-009X PY - 2011///0104 KW - Animals KW - Biomarkers KW - metabolism KW - Breast Neoplasms KW - pathology KW - Cell Division KW - drug effects KW - Dose-Response Relationship, Drug KW - Female KW - Humans KW - Indazoles KW - pharmacokinetics KW - Mice KW - Mice, Nude KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Sulfonamides N1 - Publication Type: Journal Article UR - https://doi.org/10.1124/dmd.110.032912 ER -