Salphati, Laurent

Pharmacokinetic-pharmacodynamic modeling of tumor growth inhibition and biomarker modulation by the novel phosphatidylinositol 3-kinase inhibitor GDC-0941. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Sep 2010 - 1436-42 p. digital

Publication Type: Journal Article

1521-009X

10.1124/dmd.110.032912 doi


Animals
Biomarkers--metabolism
Breast Neoplasms--pathology
Cell Division--drug effects
Dose-Response Relationship, Drug
Female
Humans
Indazoles--pharmacokinetics
Mice
Mice, Nude
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation
Protein Kinase Inhibitors--pharmacokinetics
Sulfonamides--pharmacokinetics