Benelli, Roberto

The chemopreventive retinoid 4HPR impairs prostate cancer cell migration and invasion by interfering with FAK/AKT/GSK3beta pathway and beta-catenin stability. [electronic resource] - Molecular cancer Jun 2010 - 142 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-4598

10.1186/1476-4598-9-142 doi


Anticarcinogenic Agents--pharmacology
Blotting, Western
Bone Morphogenetic Protein 2--biosynthesis
Cell Line, Tumor
Fenretinide--pharmacology
Focal Adhesion Protein-Tyrosine Kinases--metabolism
Gene Silencing
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Humans
Male
Neoplasm Invasiveness
Neoplasm Metastasis
Prostatic Neoplasms--enzymology
Proto-Oncogene Proteins c-akt--metabolism
beta Catenin--genetics