TY  - GEN
AU  - Ombetta,Jean-Edouard
AU  - Thelier,Natacha
AU  - Dong,Chang Zhi
AU  - Plocki,Stéphanie
AU  - Tsagris,Lydia
AU  - Rannou,François
AU  - Massicot,France
AU  - Djimdé,Atimé
AU  - El-Hayek,Elissar
AU  - Shi,Yiming
AU  - Heymans,Françoise
AU  - Gresh,Nohad
AU  - Chauvet,Caroline
TI  - Design of group IIA secreted/synovial phospholipase A(2) inhibitors: an oxadiazolone derivative suppresses chondrocyte prostaglandin E(2) secretion
SN  - 1932-6203
PY  - 2010///0901
KW  - Animals
KW  - Cell Line
KW  - Chondrocytes
KW  - drug effects
KW  - Dinoprostone
KW  - metabolism
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - Interleukin-1beta
KW  - pharmacology
KW  - Models, Molecular
KW  - Molecular Dynamics Simulation
KW  - Phospholipase A2 Inhibitors
KW  - Rabbits
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0010914
ER  -