TY - GEN AU - McEllin,Brian AU - Camacho,Cristel V AU - Mukherjee,Bipasha AU - Hahm,Brandon AU - Tomimatsu,Nozomi AU - Bachoo,Robert M AU - Burma,Sandeep TI - PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors SN - 1538-7445 PY - 2010///0809 KW - Animals KW - Antineoplastic Agents, Alkylating KW - pharmacology KW - Astrocytes KW - drug effects KW - Benzimidazoles KW - Brain Neoplasms KW - drug therapy KW - Cyclin-Dependent Kinase Inhibitor p16 KW - deficiency KW - DNA Damage KW - DNA Repair KW - Dacarbazine KW - analogs & derivatives KW - Glioblastoma KW - Methylnitronitrosoguanidine KW - Mice KW - Mice, Transgenic KW - PTEN Phosphohydrolase KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Recombination, Genetic KW - Temozolomide N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1158/0008-5472.CAN-09-4295 ER -