Germano, I M

Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas. [electronic resource] - Cancer gene therapy Sep 2010 - 664-74 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1476-5500

10.1038/cgt.2010.31 doi


Animals
Antineoplastic Agents, Alkylating--therapeutic use
Apoptosis
Blotting, Western
Brain Neoplasms--drug therapy
Cell Proliferation
Cells, Cultured
Combined Modality Therapy
Dacarbazine--analogs & derivatives
Drug Delivery Systems
Drug Resistance, Neoplasm--genetics
Embryonic Stem Cells--physiology
Enzyme-Linked Immunosorbent Assay
Female
Gene Transfer Techniques
Genetic Therapy
Genetic Vectors--therapeutic use
Glioma--drug therapy
Humans
Immunoenzyme Techniques
Interleukins--genetics
Mice
Mice, Nude
RNA, Messenger--genetics
Radiation, Ionizing
Radiation-Sensitizing Agents
Reverse Transcriptase Polymerase Chain Reaction
Temozolomide
Transgenes--physiology
Tumor Stem Cell Assay