Hiscutt, Emma L

Targeting X-linked inhibitor of apoptosis protein to increase the efficacy of endoplasmic reticulum stress-induced apoptosis for melanoma therapy. [electronic resource] - The Journal of investigative dermatology Sep 2010 - 2250-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1523-1747

10.1038/jid.2010.146 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Boronic Acids--pharmacology
Bortezomib
Drug Resistance, Neoplasm
Endoplasmic Reticulum--physiology
Female
Fenretinide--pharmacology
Gene Expression Regulation, Neoplastic
Genes, ras--physiology
Humans
In Vitro Techniques
Male
Melanoma--drug therapy
Middle Aged
Mutation--genetics
Nevus, Pigmented--drug therapy
Proto-Oncogene Proteins B-raf--genetics
Pyrazines--pharmacology
RNA, Small Interfering
Skin Neoplasms--drug therapy
Stress, Physiological--physiology
X-Linked Inhibitor of Apoptosis Protein--antagonists & inhibitors