TY - GEN AU - Squarize,Cristiane H AU - Castilho,Rogerio M AU - Bugge,Thomas H AU - Gutkind,J Silvio TI - Accelerated wound healing by mTOR activation in genetically defined mouse models SN - 1932-6203 PY - 2010///0907 KW - Animals KW - Cell Compartmentation KW - drug effects KW - Cell Movement KW - Enzyme Activation KW - Epithelial Cells KW - Gene Deletion KW - Intracellular Signaling Peptides and Proteins KW - metabolism KW - Keratinocytes KW - Mice KW - Models, Animal KW - PTEN Phosphohydrolase KW - deficiency KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - Sirolimus KW - pharmacology KW - Skin KW - TOR Serine-Threonine Kinases KW - Tuberous Sclerosis Complex 1 Protein KW - Tumor Suppressor Proteins KW - Up-Regulation KW - Wound Healing N1 - Publication Type: Journal Article; Research Support, N.I.H., Intramural UR - https://doi.org/10.1371/journal.pone.0010643 ER -