TY  - GEN
AU  - Leissring,Malcolm A
AU  - Malito,Enrico
AU  - Hedouin,Sabrine
AU  - Reinstatler,Lael
AU  - Sahara,Tomoko
AU  - Abdul-Hay,Samer O
AU  - Choudhry,Shakeel
AU  - Maharvi,Ghulam M
AU  - Fauq,Abdul H
AU  - Huzarska,Malwina
AU  - May,Philip S
AU  - Choi,Sungwoon
AU  - Logan,Todd P
AU  - Turk,Benjamin E
AU  - Cantley,Lewis C
AU  - Manolopoulou,Marika
AU  - Tang,Wei-Jen
AU  - Stein,Ross L
AU  - Cuny,Gregory D
AU  - Selkoe,Dennis J
TI  - Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin
SN  - 1932-6203
PY  - 2010///0907
KW  - Animals
KW  - CHO Cells
KW  - Cricetinae
KW  - Cricetulus
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - analysis
KW  - Extracellular Space
KW  - drug effects
KW  - HeLa Cells
KW  - Humans
KW  - Insulin
KW  - metabolism
KW  - Insulysin
KW  - antagonists & inhibitors
KW  - Models, Molecular
KW  - Peptide Library
KW  - Protein Binding
KW  - Signal Transduction
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0010504
ER  -