TY  - GEN
AU  - Radhakrishnan,Suresh
AU  - Miranda,Enrique
AU  - Ekblad,Maria
AU  - Holford,Alan
AU  - Pizarro,Maria Tome
AU  - Lemoine,Nicholas R
AU  - Halldén,Gunnel
TI  - Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts
SN  - 1557-7422
PY  - 2011///0321
KW  - Adenovirus E1A Proteins
KW  - genetics
KW  - Adenovirus E1B Proteins
KW  - Adenoviruses, Human
KW  - drug effects
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Cell Cycle
KW  - Cell Death
KW  - Cell Line, Tumor
KW  - Combined Modality Therapy
KW  - Docetaxel
KW  - Flow Cytometry
KW  - Gene Expression
KW  - Genes, p53
KW  - Humans
KW  - Immunoblotting
KW  - Male
KW  - Mice
KW  - Mice, Nude
KW  - Mitoxantrone
KW  - Neoplasm Transplantation
KW  - Oncolytic Virotherapy
KW  - methods
KW  - Oncolytic Viruses
KW  - Polymerase Chain Reaction
KW  - Prostatic Neoplasms
KW  - drug therapy
KW  - Retinoblastoma Protein
KW  - metabolism
KW  - Taxoids
KW  - Transplantation, Heterologous
KW  - Tumor Suppressor Protein p53
KW  - Virus Replication
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1089/hum.2010.019
ER  -