TY  - GEN
AU  - Tian,Hong-Lei
AU  - Yu,Ting
AU  - Xu,Nai-Ning
AU  - Feng,Chao
AU  - Zhou,Li-Ying
AU  - Luo,Hou-Wei
AU  - Chang,Donald C
AU  - Le,Xiao-Feng
AU  - Luo,Kathy Qian
TI  - A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway
SN  - 1872-7980
PY  - 2010///1004
KW  - Abietanes
KW  - Animals
KW  - Antineoplastic Agents, Phytogenic
KW  - chemical synthesis
KW  - Antioxidants
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Caspase 3
KW  - metabolism
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Cytochromes c
KW  - Dose-Response Relationship, Drug
KW  - Doxorubicin
KW  - Female
KW  - HL-60 Cells
KW  - HeLa Cells
KW  - Hep G2 Cells
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - Mitochondria
KW  - Neoplasms
KW  - drug therapy
KW  - Paclitaxel
KW  - Phenanthrenes
KW  - Propyl Gallate
KW  - Protein Transport
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - genetics
KW  - Reactive Oxygen Species
KW  - Receptor, ErbB-2
KW  - Solubility
KW  - Time Factors
KW  - Transfection
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
KW  - bcl-2-Associated X Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.canlet.2010.04.020
ER  -